IRX6 and hypospadias: Through case-control analysis, we found that IRX6 rs6499755 was linked to an increased risk of hypospadias (OR = 1.547, p = 0.01), especially anterior (OR = 3.579, p=0.003) and posterior hypospadias (OR = 1.737, p=0.005), which probably through recessive models (OR = 1.832, p=0.026).