Our PPI network analysis also revealed interactions between ZNF469 and CCT candidate genes, including COL5A1, COL1A1, and other genes that regulate eyeball development, such as VSX1 (causing KC and corneal dystrophy) and CHST14 (Ehlers-Danlos Syndrome candidate gene, Figure 5). Here, ZNF469 is linked to Ehlers-Danlos syndrome.