These include a high neutrophils activity and elevated levels of interleukin-1β in both BD and autoinflammatory diseases, recurrent episodes of remission and exacerbation, absence of specific autoantibody attributed to the pathogenesis of BD, in opposite to other AID, and the relationships between BD and some autoinflammatory diseases like FMF with both diseases having a particular variant of the MEFV gene [2]. Here, MEFV is linked to Behcet disease.