Decreases kidney damage biomarkers in cardiac surgery patients at high risk of AKI (Weiss et al., 2023)Attenuates tubular cell mitochondrial intrinsic apoptosis by modulating the Tgm2/HSP70/Ask1/JNK pathway in IRI-induced AKI (Thomas et al., 2022)Reduces oxidative stress in gentamicin-induced AKI in rats (Zhan et al., 2022)Protects kidney function by regulating the miRNA/PI3κ/Akt signaling pathway in IR-induced AKI (Li S.et al., 2022)Reduces OCT2 expression and the absorption of cisplatin in HK-2 cells (Kim et al., 2015). The gene discussed is MAPK8; the disease is acute kidney injury.