NPPB and apparent mineralocorticoid excess: A joint analysis of D-dimer, NT-proBNP, and troponin in acute PE (APE) by Kauppi et al. [35] demonstrated a significant HR (HR = 10.7, 95% CI: 4.1-28.0) for predicting APE relapse and mortality, highlighting the enhanced prognostic value of multi-biomarker assessment.