ACTH, adrenocorticotropic hormone; CSF, cerebrospinal fluid; EEG, electroencephalogram; EE-PALE, epileptic encephalopathy following HHV6-related PALE; HHV6, human herpes virus 6; IVMP, intravenous methylprednisolone; IVIG, intravenous immunoglobulin; MRI, magnetic resonance imaging; N/A, not applicable; OCB, oligoclonal band; PALE, post-transplant acute limbic encephalitis. The gene discussed is POMC; the disease is Epileptic encephalopathy.