RNASEK and cancer: Our findings demonstrated significant RNASEK upregulation across six cancer types: BLCA, CHOL, ESCA, HNSC, LIHC, and THCA, which aligns with previous research showing threefold higher RNASEK expression in various cancer tissues like heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas compared to normal tissues [6].