Although ALB was not directly annotated as AD-related in the databases, it is known for its antioxidant and anti-inflammatory properties [36], and evidence suggests an inverse association between blood levels of this protein and the severity of certain ADs (including systemic lupus erythematosus, myasthenia gravis or neuromyelitis optica spectrum disorder) [[19], [20], [21]]. The gene discussed is ALB; the disease is neuromyelitis optica.