In addition, several autoimmunity-related proteins are linked to coagulation (e.g., AGT, F2) and to specific ADs, such as systemic lupus erythematosus (e.g., AGT, C1S, C7, MMP2, VWF) or autoimmune rheumatic diseases (e.g., ADIPOQ, AGT, MASP1, MMP2) (Table 1). Here, C1S is linked to systemic lupus erythematosus.