FTH1 and colitis: To reveal the role of EV‐mediated communication between IECs and macrophages in the process of DSS‐induced colitis, we used the EV inhibitor GW4869 to interfere with EV release in WT and FtHVil/Vil mice overexpressing FTH in the epithelium via in vivo jetPEI (Figure 4A,B).