FTH1 and colitis: 2020; Moon et al. 2022), systemic iron homeostasis was disrupted (Figure S1H–O). Similar to human observations, total FtH was elevated in the colon of mice with DSS‐induced colitis (Figure 1G). However, FtH levels were lower in the epithelial layer (Figure 1H, quantified in 1I), while increased iron (Figure 1J) and greater co‐localization of macrophage marker F4/80 and FtH (Figure 1K,L) were observed in lamina propria.