Initially identified through a PD case/control study, large‐scale analysis of the LRRK2 locus from the Gnomad, 23andMe, and UK Biobank cohorts revealed 1455 individuals with LRRK2 heterozygous LOF variants, including frameshifts, premature stop codons, and alterations in splicing, with a population frequency of 0.48% (Whiffin et al., 2020). The gene discussed is LRRK2; the disease is Parkinson disease.