Our final major finding was that in K‐ROAD, quantitative tau staging (MTL, neo‐temporal, and temporoparietal ROIs) effectively differentiated cognitive decline across all stages (A+/T− vs. A+/Tmod+ vs. A+/Tadv+), whereas visual tau staging primarily distinguished cognitive decline between A+/T− and A+/Tadv+. Here, MAPT is linked to Mental deterioration.