Although genome-wide promoter CpG island hypermethylation of Epstein–Barr virus-associated gastric carcinoma (EBV GC) is well known, ZNF793 is rarely methylated in EBV GC but is frequently methylated in other molecular subtypes of GC, including microsatellite instability-high GC. This evidence concerns the gene ZNF793 and gastric carcinoma.