Given that SGLT2 inhibitors are associated with reduced preload, afterload, atrial size, and calcium overload, it would not be surprising to find that SGLT2 inhibitors decrease the incidence of postoperative AF in patients undergoing cardiac surgery; [5, 19, 20, 21] an association that has already been shown in large meta‐analyses with patients on chronic SGLT2 inhibition treatment [22, 23]. Here, SLC5A2 is linked to atrial fibrillation.