Additional risk factors for MPM include exposure to ionizing radiation, such as mantle radiation therapy for Hodgkin’s lymphoma, and germline mutations in the BRCA1-associated protein 1 (BAP1) gene.2 Additionally, evidence suggests that genetic variability in antioxidative defense and DNA repair, along with gene-gene interactions, may contribute to the development of malignant mesothelioma.3 The gene discussed is BAP1; the disease is malignant mesothelioma.