Based on reported biological functions, SRY-box transcription factor 6 (SOX6), apolipoprotein A4 (APOA4), SID1 transmembrane family member 2 (SIDT2), transgelin (TAGLN), and transmembrane serine protease 13 (TMPRSS13) were identified as the candidate genes associated for SIL. The gene discussed is SIDT2; the disease is squamous cell intraepithelial neoplasia.