TYK2 and COVID-19: In addition to FOXP4, other genes – such as Transmembrane Protease Serine-2 (TMPRSS2), Leucine Zipper Transcription Factor-Like-1 (LZTFL1), Solute Carrier family-6 member-20 (SLC6A20), Tyrosine Kinase-2 (TYK2), and FYVE and coiled-coil domain-containing 1 (FYCO1) – have been associated with COVID-19 outcomes, contributing to both increased risk and potential resilience.4, 5, 6