For example, urinary IGFBP7 and TIMP‐2, which induce G1 cell cycle arrest in renal epithelial cells during AKI, provide insight into glomerular or tubular damage, with IGFBP7 linked to proximal tubules and TIMP‐2 to distal tubules (Emlet et al., 2017). The gene discussed is IGFBP7; the disease is acute kidney injury.