For example, biseugenol B was found to induce apoptosis in PC3 prostate cancer cells by inhibiting NF-κB translocation and altering the Bax/Bcl-2 ratio, leading to cytochrome c release and subsequent caspase activation (Abbaspour Babaei et al., 2017). This evidence concerns the gene NFKB1 and Familial prostate cancer.