RSAD2, also known as viperin, and the adjacent gene CMPK2, which are both directly implicated in ddhCTP production1, were amongst the top 20 most correlated genes in both infections, with correlation coefficients ranging from 0.840 to 0.885 (p-values < 0.0001, Supplementary Fig. 5). Here, CMPK2 is linked to infection.