AKT1 and pulmonary fibrosis: Pathways enriched in track FibAlv-4 include the following: in path A, collagen and extracellular matrix (ECM) pathways72; in path B, the PI3K-Akt-mTOR signalling pathway and the focal adhesion pathway (both are important in lung fibrosis)73–75 (Fig. 3b); and in path C, SLIT/Robo signalling pathway, less studied but with a potential role in regulation of fibrosis64,76.