CCL20 and Crohn disease: At a cutoff value of 0.63 pg/mL or higher, serum CCL20 levels demonstrated optimal diagnostic performance in distinguishing patients with Crohn’s disease from HCs [AUC (95% CI): 0.65 (0.56, 0.74), p = 0.0010; sensitivity: 0.94 (0.89, 0.97), specificity: 0.38 (0.26, 0.52), positive predictive value (PPV): 0.81 (0.75, 0.86), negative predictive value (NPV): 0.70 (0.51, 0.84), accuracy: 0.80 (0.74, 0.85); Fig. 1C].