However, all patients with Crohn’s disease were genotyped for the three main Crohn’s disease-associated NOD2 mutations [p.Arg702Trp (rs2066844), p.Gly908Arg (rs2066845), and p.Leu1007fsX1008 (rs2066847)], and any potential influence of NOD2 genotype status on serum CCL20 levels could be ruled out through linear regression modeling. Here, NOD2 is linked to Crohn disease.