However, cholecalciferol supplementation tended to lower CCL20 levels in patients with Crohn’s disease [univariable: β (95% CI) =  − 0.188 (− 0.374, − 0.003), p = 0.047; multivariable: β (95% CI) =  − 0.175 (− 0.360, 0.010), p = 0.063; Table 3]. The gene discussed is CCL20; the disease is Crohn disease.