Darwish et al.27 elicited that levels of IL-5, IL-6, IL1-ß, TNF α, TLR4 and Tollip (Toll interacting protein) were shown to be substantially more up-regulated in postpartum disorder-affected sheep than in resistant ones, although the patterns of SOD and CAT genes showed the reverse tendency. Here, TLR4 is linked to puerperal disorder.