Parkinson’s disease (PD) is the most common neurodegenerative movement disorder, with its classic motor symptoms the result of progressive loss of dopamine producing neurons in the midbrain, while broader neuronal dysfunction and symptomology are associated with pathological protein depositions of misfolded alpha-synuclein into cytoplasmic inclusions termed Lewy bodies1. The gene discussed is SNCA; the disease is Parkinson disease.