PRKN and Parkinson disease: Several pathological mutations in the genes coding for PTEN-induced Kinase 1 (PINK1), Parkin, Leucine Rich Repeat Kinase 2 (LRRK2), glucocerebrosidase 1 (GBA1) and DJ-1 or PARK7 (Parkinson disease protein 7) were subsequently reported and established the genetic link to PD.