BAG3 and cerebral cavernous malformation: However, no significant association was found between late-onset CCM risk and PAV carrier status in TTN exons with PSI greater than 0.82, TTN exons with PSI greater than 0.82, in the A-band region, or in BAG3 (eTable 8 in Supplement 1) or in African ancestry survivors (eTable 9 in Supplement 1).