BAG3 and cerebral cavernous malformation: In addition to rs3829746 and rs2234962, we evaluated 31 common missense SNVs within TTN and 1 SNV within BAG3. Of these, 12 SNVs within TTN showed nominally significant (ie, P = .02 to .05) associations with late-onset CCM risk in the combined sample of European ancestry survivors, as shown in eTable 1 in Supplement 1.