CRP and melanoma: As suggested by our data, higher CRP showed remarkable relation to dismal OS (HR = 2.26, 95% CI = 1.89-2.71, <i>p</i> < 0.001) and inferior PFS (HR = 1.84, 95% CI = 1.13-2.98, <i>p</i> = 0.014) of melanoma patients.