SYNPO and diabetic kidney disease: Previous studies have shown that RIPK3 expression is elevated in the glomeruli and renal tubules of patients with DKD,[17, 18] and a portion of the elevated RIPK3 in the glomeruli can co‐localize with the podocyte marker protein synaptopodin.[13] Meanwhile, the results of the present study found that podocyte RIPK3 levels were positively correlated with the UACR of DKD patients, suggesting that podocyte RIPK3 may influence the progression of DKD, which is consistent with the findings of podocyte‐specific RIPK3 KO in mice.