Previous studies have shown that RIPK3 is involved in HG‐induced podocyte injury in vitro.[13, 14] Besides, a recent study using RIPK3‐KO mice with HFD‐induced diabetes demonstrated that RIPK3 KO alleviated podocyte injury and proteinuria.[17] However, since RIPK3 is widely expressed and elevated in the glomeruli and renal tubules of DKD patients,[17, 18] the renoprotective effects did not exclude the influence of other cell types. Here, RIPK3 is linked to diabetic kidney disease.