Consistent with the fact that PcRD18 suppresses various immune responses, i.e., the ROS burst, MAPK activation, PR gene expression, and INF1‐induced cell death, all of which are positively regulated by GSNOR (Figure 2), the PcRD18‐IM mutant indeed lost the ability to modulate SlGSNOR activity, NO homeostasis, immune response and to promote infection (Figure 7D–I). Here, TMEM37 is linked to infection.