GSDMD and viral infectious disease: Given that we observed GSDMD cleavage during EMCV infection (Figure 1n), a finding also evident in IAV infection,[21] and considering that HEK293T cells, which lack inflammasome components, do not undergo GSDMD cleavage upon viral infection (Figure S2g, Supporting Information), we hypothesized that the enhanced IFN‐I signaling observed in GSDMD‐KO mice might be attributed to GSDMD cleavage fragments.