GSDMD and viral infectious disease: However, Caspase‐3, activated by EHEC Stx, subsequently cleaves the GSDMD‐NT produced by Caspase‐11, rendering it nonfunctional.[18] While it is undeniable that inflammasome activation plays a critical role in defending against viral infections, the possibility of viruses utilizing sophisticated regulatory mechanisms to counteract the antiviral effects of inflammasomes remains unexplored.