Viral infections, including those by IBDV, VSV, AIV, and NDV, can activate inflammasomes like NLRP3 (leading to Caspase‐1 activation and GSDMD cleavage)[43] or directly induce GSDME cleavage.[44] However, the impact of GSDMD on interferon signaling appears complex. Here, NLRP3 is linked to viral infectious disease.