Similarly, for the broader BD-D vs. HC comparison, proteins such as JUN, FOSB, and NFKBIA were identified as playing crucial roles in BD, underscoring the complex interplay of signaling pathways and inflammatory processes in the disorder (Figure 4C).Among the 91 co-DEGs, JUN and FOSB emerged as core components of the network (Figure 4D), reinforcing their potential significance across different phases of BD and suggesting a consistent role in the disorder’s molecular basis. This evidence concerns the gene JUN and Behcet disease.