By univariate analysis, we found that age, race, sex, marital status, education level, weight, WC, BMI, height, SBP, DBP, HbA1c, FPG, insulin, albumin, creatinine, BUN, TC, TG, LDL, HDL, DM status, smoking status, hypertension status and hyperlipidemia status were associated with the risk of developing HUA (all p < 0.05). The gene discussed is INS; the disease is Hypertension.