After adjusting for age, race, gender, marital status, education level, WC, BMI, insulin, albumin, hypertension status, DM status, smoking status, drinking status, hyperlipidemia status, as BUN increased, the risk of HUA increased significantly in both men (OR: 1.19, 95% Cl:1.16~1.23) and women (OR:1.32, 95% Cl:1.32 (1.28~1.37)(all p < 0.001). Here, INS is linked to hypertensive disorder.