In the present study, 35.9% of GFAP-A patients developed epileptic seizures during the disease course (with significantly more males than females), and our proportion of patients was significantly higher than that of pediatric and adult GFAP-A patients with epileptic seizures (10–20%), as reported in the literature (10, 11, 13, 14). The gene discussed is GFAP; the disease is Seizure.