In patients with polycystic ovarian syndrome (PCOS), curcumin reduced FBG (WMD: 3.618; 95%CI: 5.165, −2.071; I2 = 20.4%), and insulin levels (WMD: 1.834; 95%CI: 2.701, −0.968; I2 = 8.4%) (Shen et al., 2022). The gene discussed is INS; the disease is polycystic ovary syndrome.