CD14 high monocytes displayed the highest levels of increased platelet aggregates (15.22% ± 10.85% in healthy donors vs. 31.72% ± 22.98% in HNSCC patients), followed by neutrophils (9.27% ± 5.54% vs. 17.42% ± 10.19%) and T cells (3.18% ± 0.84% vs. 4.53% ± 1.87%), whereas eosinophil-platelet aggregates were not significantly altered (14.38% ± 9.49% vs. 26.43% ± 24.42%) (Figures 1A–D). This evidence concerns the gene CD14 and head and neck squamous cell carcinoma.