P2RY12 and COVID-19: Besides GPIIb/IIIa and COX-1 inhibitors, the P2Y12 antagonist ticagrelor has shown only a slight effect on P-selectin expression in a COVID-19 model (Schrottmaier et al., 2021), while clopidogrel was reported to only marginally reduce TRAP-induced P-selectin expression and PLA formations (Xiao and Théroux, 2004).