Additionally, while we observed increased P-selectin expression, elevated PLAs in HNSCC patients, and a potent reduction of P-selectin expression and PLA formation following 1,8-cineole treatment, the study did not explore whether these reductions in PLA formation or P-selectin expression correlate with clinical outcomes, such as tumor progression, response to therapy, or survival. Here, SELP is linked to head and neck squamous cell carcinoma.