For example, a study demonstrated that celastrol‐loaded albumin NPs effectively targeted mesangial cells to treat mesangioproliferative glomerulonephritis.[184] In addition, human serum albumin NPs with a size of 95 nm maximize mesangial cell uptake through caveolae‐and clathrin‐mediated pathways and macropinocytosis. This evidence concerns the gene ALB and glomerulonephritis.