JAK2 and neoplasm: Besides, the typical function of DDAH1 is to regulate intracellular NO concentration by modulating ADMA levels.[11] Furthermore, NO concentrations are linked to poor survival and the activation of tumor‐related pathways in various cancers, including breast, colon, and gastric cancers.[] However, our findings showed that altering intracellular NO concentration, either by increasing or decreasing it, did not significantly affect the activation of the EGFR‐JAK2‐STAT3 pathway in NPC cells.