The phenotypic similarities between PPM1F-deficiency and filaminA-deficiency are not restricted to the murine system: Accumulation of neural progenitor cells in the ventricular region, as seen in PPM1F-deficient mouse embryos, is a hallmark of periventricular heterotopia (PH), a human condition associated with filaminA mutations [75]. The gene discussed is PPM1F; the disease is Periventricular heterotopia.