Since a recent study described MAPK hyperactivation as a new hallmark of type A and AB thymomas, the here identified direct interaction of two cluster members (miR-520a-3p, miR-520c-3p) with DUSP2 as well as of miR-29 cluster members might contribute to MAPK activation via repression of negative regulators [102]. This evidence concerns the gene DUSP2 and thymoma.