APOE and atherosclerosis: In our search for potential diagnostic biomarkers related to atherosclerosis, we observed a significant increase in the levels of four phosphatidylcholines (PC): P-18:0/16:0, P-18:0/22:4 (7Z, 10Z, 13Z, 16Z), P-18:1 (9Z)/16:1 (9Z), and P-18:1 (11Z)/22:5 (4Z, 7Z, 10Z, 13Z, 16Z); four sphingomyelins (SM): d16:1/24:1 (15Z), d18:1/20:0, d18:1/14:0, and d18:1/16:0; trimethylamine-N-oxide; and stearoyl carnitine in the ApoE−/− group compared to the WT group.