PDXK and cardiovascular disorder: FUMA annotation identified 3 independent genomic loci in this region, each of which is an eQTL for PDXK, RRP1B, and HSF2BP. Each of the genes has been previously associated with risk of diseases for which serum lipids concentration is a key risk factor: PDXK and RRP1B with coronary artery disease [75] and HSF2BP with cardiovascular disease [76].