The search string used was as follows: (“Microglia” OR “astrocytes” OR “T lymphocytes” OR “B lymphocytes” OR “NK cells” OR “CD4+ T cells” OR “CD8+ T cells” OR “Th17 cells” OR “Th1 cells” OR “Treg cells”) AND (“neurodegenerative diseases” OR “Parkinson’s disease” OR “Alzheimer’s disease” OR “amyotrophic lateral sclerosis” OR “multiple sclerosis” OR “neuroinflammation”). The gene discussed is CD8A; the disease is Alzheimer disease.