One set included Tph cells (T11), activated memory B/early plasmablasts (B10), plasmablasts (B8, B11), and CD8+granzyme B+Ki67+ (T13) cells, comprising a set of T cells and B cells with a shared proliferative state (Ki67+), resembling subsets expanded in patients with newly diagnosed SLE (50) (Figure 3A). The gene discussed is CD8A; the disease is systemic lupus erythematosus.