Further, compared to the oe‐NC+M2pep‐Cs NPs/Plerixafor group, the number of Th1 cells significantly decreased; while, the number of Th2 cells significantly increased in the tumor tissues of mice in the oe‐CXCR4+M2pep‐Cs NPs/Plerixafor group (Figure S13C,D, Supporting Information). Here, CXCR4 is linked to neoplasm.