Compared to the oe‐NC+M2pep‐Cs NPs/Plerixafor group, the mRNA levels of CD80, IL‐1β, and IL‐6 were significantly downregulated, and the mRNA levels of CD206 and IL‐10 were significantly upregulated in the tumor tissues of mice in the oe‐CXCR4+M2pep‐Cs NPs/Plerixafor group (Figure 8G). This evidence concerns the gene CXCR4 and neoplasm.