These animals did not show increased liver weight nor liver failure, although they showed signs of liver injury (ie, increased ALT and AST levels), renal failure (ie, increased creatinine levels), and higher INR (indicative of coagulation failure) without evidence of brain failure (Supplemental Figure S3, http://links.lww.com/HC9/C23). The gene discussed is GPT; the disease is Renal insufficiency.