MYC is a well-known oncogene involved in regulating processes critical to tumorigenesis, such as angiogenesis, cell adhesion, metabolism, and immune evasion, thereby promoting malignancy and tumor aggression.46,47 Our finding suggests that alterations in the antigen processing and presentation pathway may accelerate cancer progression by activating oncogenic pathways.48 This connection underscores the potential for aberrations in immune-related pathways to influence not just tumor biology but also therapeutic responses. This evidence concerns the gene MYC and cancer.