PDLIM5 and cancer: In line with our findings, many studies have emphasized that YAP facilitates tumor progression by mediating heterologous communication between tumor cells and immune cells via paracrine‐acting factors.[67, 68, 69] The macrophage recruitment, as well as the M2 polarization‐promoting function of YAP in cancer, has also been well established.[70, 71, 72] The reason why ENH‐induced YAP activation does not affect cell proliferation may be that when ENH is knocked down or overexpressed, certain unknown molecules are also altered.