PDLIM5 and neoplasm: It is well known that tumor cells interact with endothelial cells through secretory proteins to enhance angiogenesis.[46, 47, 48] However, we found the CM from ENH‐overexpressing or knockdown LUAD cells did not alter the angiogenic ability of endothelial cells, suggesting that ENH may promote angiogenesis by remodeling the composition of immune cells.