CD8A and neoplasm: The index low-risk cluster exhibited an elevated incidence compared to the high-risk category, which includes the majority of immune cells such as B cells, CD8+ T cells, dendritic cells (DCs), interstitial (i)DCs, plasmacytoid (p)DCs, macrophages, neutrophils, T helper cells (Th1 and Th2), T follicular helper (Tfh) cells, tumor-infiltrating lymphocytes (TILs), and regulatory T cells (Tregs) (Fig. 8E, P < 0.001).