15 genes (CASP6, BAK1, CASP3, BAX, CHMP4C, GPX4, CYCS, CASP8, CHMP2A, TREM2, NLRP2, SCAF11, GSDMD, IL18, and CHMP4A) were upregulated and 11 genes (NLRP1, SIRT1, NOD1, CARD8, DPP8, IRF2, NAIP, TIRAP, PJVK, PRKACA, and CHMP2B) were downregulated in tumor samples. The gene discussed is IL18; the disease is neoplasm.