While elevated DSN1 expression is associated with poor prognosis in numerous cancers, including ACC, BRCA, HNSC, KICH, KIRP, LGG, LIHC, MESO, PRAD, and UVM, it paradoxically correlates with a favorable prognosis in others, such as CESC, KIRC, READ, STAD, and THYM. The gene discussed is DSN1; the disease is cancer.