STC2 positively correlates with immune scores in BLCA, KICH, KIRC, MESO, pheochromocytoma and paraganglioma (PCPG), PRAD and UVM; but negatively correlates with immune scores in BRCA, CESC, LGG, LUAD, LUSC, TGCT, THCA and UCEC (Supplementary Figure 4A). Here, STC2 is linked to hereditary pheochromocytoma-paraganglioma.