Consistent with the protein level changes, quantitative real-time PCR (qPCR) analysis shows that PA significantly downregulates the mRNA expression levels of the crucial anti-ferroptosis genes GPX4, SLC7A11, and NRF2 in both NSCLC cell lines in a dose-dependent manner (Figures 5B,C). Here, GPX4 is linked to non-small cell lung carcinoma.